Ulrich Steidl Selected Research

proto-oncogene protein Spi-1

1/2019	Transcriptional regulators CITED2 and PU.1 cooperate in maintaining hematopoietic stem cells.
12/2017	Pharmacological inhibition of the transcription factor PU.1 in leukemia.
10/2015	Minimal PU.1 reduction induces a preleukemic state and promotes development of acute myeloid leukemia.
8/2008	PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element.
11/2006	Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells.
1/2006	Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1.

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Ulrich Steidl Research Topics

Disease

28	Neoplasms (Cancer) 12/2021 - 07/2002
22	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2020 - 06/2005
14	Leukemia 01/2021 - 06/2005
12	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 12/2021 - 01/2007
6	Thrombocytopenia (Thrombopenia) 10/2020 - 10/2009
4	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 11/2006 - 08/2004
3	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022 - 11/2017
3	Hematologic Neoplasms (Hematological Malignancy) 01/2021 - 07/2002
3	Primary Myelofibrosis (Myelosclerosis) 01/2019 - 01/2017
3	Multiple Myeloma 01/2018 - 02/2006
2	Adenocarcinoma 01/2022 - 07/2010
2	Carcinogenesis 01/2022 - 12/2006
2	Anemia 10/2021 - 02/2011
2	Neutropenia 10/2021 - 10/2006
2	Breast Neoplasms (Breast Cancer) 01/2020 - 07/2010
2	Bone Marrow Failure Disorders 12/2018 - 02/2011
2	Disease Progression 01/2017 - 01/2017
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2016 - 04/2010
2	Polycythemia Vera 02/2013 - 04/2010
2	Lung Neoplasms (Lung Cancer) 12/2006 - 01/2005
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2006 - 01/2006
1	Hypotension (Low Blood Pressure) 10/2021
1	Chromosome Breakage 01/2021
1	Myeloid Leukemia (Leukemia, Myelocytic) 01/2021
1	Cardiomyopathies (Cardiomyopathy) 01/2020
1	Necrosis 01/2020
1	Aplastic Anemia (Anemia, Hypoplastic) 10/2019
1	Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated) 01/2019
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2019
1	Paraproteinemias (Monoclonal Gammopathy) 03/2013
1	Thrombocytosis (Thrombocythemia) 02/2013
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 10/2012
1	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 07/2012
1	Myeloproliferative Disorders (Myeloproliferative Disorder) 01/2012
1	Hodgkin Disease (Hodgkin's Disease) 03/2011
1	Prostatic Neoplasms (Prostate Cancer) 07/2010

Drug/Important Bio-Agent (IBA)

6	eltrombopag FDA Link 10/2019 - 10/2009
6	proto-oncogene protein Spi-1IBA 01/2019 - 01/2006
6	Transcription Factors (Transcription Factor)IBA 11/2017 - 06/2005
4	Proteins (Proteins, Gene)FDA Link 01/2018 - 01/2017
3	RNA (Ribonucleic Acid)IBA 01/2022 - 03/2011
3	ChromatinIBA 01/2021 - 11/2017
3	CytosineIBA 01/2019 - 01/2017
3	5-hydroxymethylcytosineIBA 01/2019 - 09/2013
3	Thrombopoietin ReceptorsIBA 12/2018 - 10/2009
3	Biological ProductsIBA 11/2018 - 04/2015
3	ParaffinIBA 11/2006 - 01/2005
3	Formaldehyde (Formol)FDA Link 11/2006 - 01/2005
2	Interleukin-1 Receptor Accessory ProteinIBA 01/2022 - 01/2018
2	CateninsIBA 12/2021 - 01/2017
2	Phosphotransferases (Kinase)IBA 12/2019 - 10/2006
2	LY-2157299IBA 12/2019 - 02/2011
2	Protein Isoforms (Isoforms)IBA 01/2019 - 01/2019
2	Janus Kinase InhibitorsIBA 01/2019 - 04/2010
2	IronIBA 12/2018 - 07/2012
2	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 11/2015 - 02/2015
2	LigandsIBA 03/2011 - 01/2007
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 12/2006 - 08/2004
2	fragile histidine triad proteinIBA 11/2006 - 01/2005
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 11/2006 - 01/2005
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 10/2006 - 02/2006
2	pegfilgrastim (Neulasta)FDA Link 10/2006 - 02/2006
1	CA-4948IBA 01/2022
1	Interleukin-1 Receptor-Associated KinasesIBA 01/2022
1	Alkaline PhosphataseIBA 10/2021
1	Peptides (Polypeptides)IBA 10/2021
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2021
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020
1	Surface Antigens (Surface Antigen)IBA 01/2020
1	Lactic Acid (Lactate)FDA LinkGeneric 11/2019
1	Trans-Activators (Trans-Acting Factor)IBA 01/2019
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2019
1	Small Interfering RNA (siRNA)IBA 01/2019
1	PF 3758309IBA 01/2019
1	Aurora Kinase AIBA 01/2019
1	p21-Activated KinasesIBA 01/2019
1	Chelating AgentsIBA 12/2018
1	CarcinogensIBA 01/2018
1	hydrogen sulfite (bisulfite)IBA 11/2017
1	CytokinesIBA 01/2017
1	Nuclear Proteins (Protein, Nuclear)IBA 01/2017
1	A-Form DNA (A-DNA)IBA 01/2017
1	CalreticulinIBA 04/2016
1	pexmetinibIBA 01/2016
1	p38 Mitogen-Activated Protein KinasesIBA 01/2016
1	RNA Helicases (RNA Helicase)IBA 05/2015
1	Lenalidomide (CC 5013)FDA Link 12/2014
1	Histone Deacetylase InhibitorsIBA 08/2014
1	Cytarabine (Cytosar-U)FDA LinkGeneric 10/2012
1	RicinIBA 10/2012
1	combotoxIBA 10/2012
1	Immunotoxins (Immunotoxin)IBA 10/2012
1	NF-E2 Transcription FactorIBA 01/2012
1	GTP Phosphohydrolases (GTPases)IBA 07/2011
1	MHC class II transactivator proteinIBA 03/2011
1	coactivator-associated arginine methyltransferase 1IBA 07/2010

Therapy/Procedure

16	Therapeutics 01/2021 - 12/2003
2	Drug Therapy (Chemotherapy) 10/2019 - 10/2006
2	Transplantation 12/2017 - 05/2004
1	Ligation 03/2013